For US Healthcare Professionals Important Safety Information Full Prescribing Information

Manufacturing

The Proven Manufacturing Process of CroFab Ensures Only the Most Effective and Highest Quality Venom-Specific Antibodies1,2

Watch Alex Garrard, Clinical Toxicologist and Medical Science Liaison, discuss the manufacturing process for CroFab.


Follow the Manufacturing Process for CroFab

Hold the cursor over highlighted steps of the manufacturing process to learn how CroFab is specifically manufactured to ensure the safe and effective management of envenomation by pit vipers native to the United States.

Steps of the manufacturing process for CroFab
Vial of CroFab

Four monospecific antivenoms are combined to become CroFab.

CroFab safety profile icon

CroFab safety is backed by more than 20 years of clinical experience1

View the Safety Profile
CroFab efficacy checkmark icon

CroFab is clinically proven to achieve initial control of envenomation1

Examine the Data
IgG antibody icon

CroFab rapidly binds to and neutralizes venom toxins1

See the MOA
REFERENCES

1. CroFab® [prescribing Information]. BTG International Inc. August 2018. 2. Data on file. BTG International Inc. 3. Alvarenga LM, Zahid M, di Tommaso A, et al. Engineering venom’s toxin-neutralizing antibody fragments and its therapeutic potential. Toxins. 2014;6(8):2541-2567. 4. Laustsen AH, Gutiérrez JM, Knudsen C, et al. Pros and cons of different therapeutic antibody formats for recombinant antivenom development. Toxicon. 2018;146:151-175. 5. WHO Expert Committee on Biological Standardization. WHO Technical Report Series, No. 1004, Annex 5; 2017. Accessed September 10, 2021. https://www.who.int/biologicals/WHO_TRS_1004_web.pdf