For US Healthcare Professionals Important Safety Information Full Prescribing Information
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Control With Confidence

The only antivenom derived from native US pit vipers to treat envenomations from all species of North American pit vipers1

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Strength and Speed When You Need It Most

North American pit vipers across the United States icon

Clinically Relevant

Derived from geographically and clinically relevant US snakes1,2

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Venomics Approach
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Specifically Engineered

Designed with a spectrum of small, venom-specific protein (Fab) fragments1,3

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Proven Efficacy

Halted all clinically important effects of envenomation, with Level 1 evidence specifically for copperhead envenomation1,4

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Antivenom for Rattlesnakes, Cottonmouths, and Copperheads

Dosing for Initial and Sustained Control of Envenomation

Administer CroFab as soon as possible to prevent clinical deterioration1

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CroFab in Clinical Practice – Hear Real Patient Experiences


1. CroFab®. Prescribing information. BTG International Inc.; August 2018. 2. WHO Expert Committee on Biological Standardization. WHO Technical Report Series, No. 1004, Annex 5; 2017. Accessed September 13, 2023. 3. Laustsen AH, María Gutiérrez J, Knudsen C, et al. Pros and cons of different therapeutic antibody formats for recombinant antivenom development. Toxicon. 2018;146:151-175. 4. Gerardo CJ, Quackenbush E, Lewis B, et al. The efficacy of Crotalidae polyvalent immune Fab (ovine) antivenom versus placebo plus optional rescue therapy on recovery from copperhead snake envenomation: a randomized, double-blind, placebo-controlled, clinical trial. Ann Emerg Med. 2017;70(2):233-244.